I-Pharmaceutical Intermediate Helper 2-MeTHF

2{{2}I-Methyltetrahydrofuran (2-i-MeTHF) lulwelo olucacileyo olunempawu ye-ether{5}}efana nevumba, isetyenziswa ngokubanzi njengesinyibilikisi esikhethekileyo kwi-organic synthesis. Ithathwe kwi-biomass evuselelekayo, inika enye indlela eco-friendly kunye neendleko ezifanelekileyo kwizinyibilikisi eziqhelekileyo ezifana ne-tetrahydrofuran (THF), i-diethyl ether, kunye ne-dichloromethane. Xa kuthelekiswa ne-THF, i-2-MeTHF inendawo yokubilisa ephezulu, ubutyhefu obusezantsi, kunye nokuncipha kokunyibilika emanzini, okunegalelo kubuchule obuphuculweyo bokutsalwa kunye nokusebenza okuphuculweyo kuzo zombini iisetingi zemizi-mveliso nezaselabhu. Iimpawu zayo ze-hydrophobic, kunye neempawu zomzimba ezixhamlayo, zenza ukuba i-solvent ixabiseke kwizinto ezizinzileyo kunye nezenzo zekhemistri eluhlaza.

Kwimveliso yamayeza aphakathi, i-2-i-MeTHF idlala indima ebalulekileyo. Isetyenziswa ngokubanzi njengendlela yokusabela kwiinkqubo ezahlukeneyo ze-organic synthesis. Iimpawu zayo ezizodwa zokunyibilika zivumela ukuchithwa okusebenzayo kwazo zombini i-organic substrates kunye ne-organometallic reagents, ukukhuthaza amazinga okuphendula kunye nokuphucula izivuno. Ukongeza, ukuguquguquka okuphantsi kunye nokuphinda kusetyenziswe kwakhona kuyenza ilungele imveliso yomgangatho woshishino, ukunciphisa impembelelo yokusingqongileyo kunye neendleko zemveliso.

Igama lemveliso	I-Pharmaceutical intermediate helper 2-MeTHF|I-2-methyltetrahydrofuran CAS 96-47-9
INOMBOLO YECAS.	96-47-9
Amagama aphambili	I-2-Methyl tetrahydrofuran, i-2-MeTHF yamachiza, i-Pharmaceutical intermediate helper 2-MeTHF
Ifomula yeemolekyuli	C5H10O
Inombolo yeHS	2932190090
Ifomula yoLwakhiwo

1. Imisebenzi enguNdoqo kunye nezinto eziluncedo

• Ucoceko olukhethekileyo (Mkhulu kune okanye ilingana ne-99.5%) kunye ne-ultra-isinyithi esisezantsi (Ngaphantsi okanye ilingana no-0.1 ppb), iqinisekisa ukuthotyelwa kwe-ICH Q3D kwiisyntheses ezinovakalelo.
• Ukunyibilika kwamanzi aphantsi kunye nokuzinzisa kwe-BHT, ukunciphisa ukubunjwa kweperoxide kunye nobungozi bokudubula.
• Iqondo eliphezulu lokubilisa (i-80 degree) kune-THF (i-66 degree) okanye i-diethyl ether (i-35 degree), ukunciphisa ukutsha kunye nokuvumela ukuphatha ngokukhuselekileyo.
• I-44% esezantsi ye-carbon footprint vs.

2. Izicelo eziPhambili zoXhobo

• Grignard Reactions
• Izisombululo: Izivuno eziphantsi kunye neemfuno ezingqongqo ze-anhydrous.
• I-Advanteji: Ulungelelwaniso olungenamandla lunyusa izivuno ze-reagent ukuya kwi-98% (vs{1}}% kwi-ether) kwaye inyamezela Ngaphantsi okanye ilingana ne-0.1% yamanzi, ukusika iindleko zokumisa.
• Imeko yokusetyenziswa: I-Chloroquine synthesis (i-42% isabela ngokukhawuleza, i-92% isivuno).
• Phezulu -AbaPhakathi bePurity
• Izisombululo: Ukungcoliswa kwesinyithi kwi-catalysts / APIs.
• I-advanteji: Kufuphi{0}}zero imikhondo yesinyithi iqinisekisa ukuthotyelwa kwemathiriyeli ye-OLED kunye namayeza okubulala iintsholongwane (umzekelo, i-cephalosporins).

I-2-MeTHF ijongana ngqo namanqaku eentlungu kwishishini le-pharma:

1. Ukhuseleko: I-BHT ukunyanzeliswa kweeperoxides kunciphisa ugcino / ingozi yezothutho.

2. Ukusebenza kakuhle: Ukunyamezelana kwamanzi kunye nokuveliswa okulula kokulula.

3. Uzinzo: {1}ubungqina obusekwe kwimvelaphi yekamva-ubungqina obuchasene noluhlu lweerhafu zekhabhoni (umzekelo, i-EU CBAM).

4. Ukubonelela: I-15,000-ton / ngonyaka umthamo (Shandong Yino) iqinisekisa ukuhambelana kwebhetshi kunye nokuhanjiswa kwehlabathi jikelele.

Itywinwe: 180kg Igubu okanye 20mt itanki ISO

Ukuba ufuna iisampuli okanye ubungakanani obuncinci be-2-Methyltetrahydrofuran (2-MeTHF), sinikezela ngeendlela ezahlukeneyo zokupakisha ukuze zihambelane neemfuno zakho.